June 2010

Secondary changes allow spread of oseltamivir resistant influenza virus

6 Comments / Basic virology, Information / By

The influenza virus neuraminidase (NA) protein is required for virus release from the cell, a property exploited by the antiviral drugs oseltamivir (Tamiflu) and zanamavir (Relenza). During clinical testing of oseltamivir in 2001, some individuals shed drug-resistant viruses with an amino acid change from histidine to tyrosine (H274Y) in NA. Such viruses are not inhibited …

Secondary changes allow spread of oseltamivir resistant influenza virus Read More »

TWiV 86: Dark matter with Dr. Eric Delwart

2 Comments / This Week in Virology / By

Hosts: Vincent Racaniello, Rich Condit, and Eric Delwart In episode #86 of the podcast This Week in Virology, Vincent and Rich travel to the Blood Systems Research Institute in San Francisco to speak with Eric Delwart about his work on virus discovery. This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 …

TWiV 86: Dark matter with Dr. Eric Delwart Read More »

A new target for hepatitis C virus

5 Comments / Basic virology, Information / By

When infection with hepatitis C virus goes from acute to chronic, severe liver disease may occur which requires organ transplantation. Nearly 200 million people are chronically infected with HCV, necessitating approaches to preventing and treating infections. No HCV vaccine is available, and current antiviral therapy consists of administration of interferon plus ribavirin, a combination that …

A new target for hepatitis C virus Read More »

TWiV 85: Hepatitis C virus with Professor Michael Gale

2 Comments / This Week in Virology / By

Hosts: Vincent Racaniello and Michael Gale On episode 85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses. This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo. …

TWiV 85: Hepatitis C virus with Professor Michael Gale Read More »

XMRV, prostate cancer, and chronic fatigue syndrome

12 Comments / Basic virology, Information / By

Robert H. Silverman, one of the authors on the study implicating the new human retrovirus XMRV as an etiologic agent of chronic fatigue syndrome, has written an excellent review article on the current status of research on the virus. The article is behind a paywall at Nature Reviews Urology, so I’ll provide a summary of …

XMRV, prostate cancer, and chronic fatigue syndrome Read More »

TWiP 11: One times three million

5 Comments / This Week in Parasitism / By

Hosts: Vincent Racaniello and Dickson Despommier On episode 11 of the podcast “This Week in Parasitism”, Vincent and Dickson continue their discussion of malaria, with emphasis on clinical aspects of the disease. [powerpress url=”http://traffic.libsyn.com/twip/TWiP011.mp3″] Click the arrow above to play, or right-click to download TWiP is brought to you by the American Society for Microbiology …

TWiP 11: One times three million Read More »

Scroll to Top