The purpose of this blog is to teach you about viruses and viral disease. This topic is not one that everyone understands, yet nearly everyone would like to. I was most disturbed when the Secretary of Health and Human Services, Tommy G. Thompson, referred to the anthrax bacillus as a virus. That incident crystallized in my mind the need to better educate the public about viruses.
I am your host at virology blog – Vincent Racaniello Ph.D., Professor of Microbiology & Immunology in the College of Physicians and Surgeons of Columbia University. Why am I qualified to teach you virology? I have done laboratory research on viruses since 1975, when I entered the Ph.D. program in Biomedical Sciences at Mt. Sinai School of Medicine of the City University of New York. My thesis research, in the laboratory of Dr. Peter Palese, was focussed on influenza viruses. That’s me in the black and white photo below, taken in 1977. Yes, I’ve changed.
In 1979 I joined the laboratory of Dr. David Baltimore at Massachusetts Institute of Technology, where I did postdoctoral work on poliovirus. The moratorium on cloning full-length viral genomes had just been lifted, so I proceeded to make a DNA copy of poliovirus RNA, using the enzyme reverse transcriptase. I cloned this DNA into a bacterial plasmid and determined the nucleotide sequence of the poliovirus genome. In an exciting advance, I found that a DNA copy of poliovirus RNA is infectious when introduced into cells. This was the first demonstration of infectivity of a DNA copy of an animal RNA virus, and it permitted previously unthought of genetic manipulations of the viral genome. Today infectious DNA clones are used to study most viruses.
In 1982 I joined the faculty in the Department of Microbiology at Columbia University College of Physicians & Surgeons in New York City. There I established a laboratory to study viruses, and to train other scientists to become virologists. Over the years we have studied a variety of viruses including poliovirus, echovirus, enterovirus 70, rhinovirus, and hepatitis C virus. As principal investigator of my laboratory, I oversee the research that is carried out by Ph.D. students and postdoctoral fellows. I also teach virology to undergraduate students, as well as graduate, medical, dental, and nursing students.
Since I think about viruses every day, and I have always been interested in teaching others about viruses, this blog seemed to be an ideal forum to convey some of my knowledge on this topic.
After starting this blog, I became interested in using ‘new media’ (internet-based media) to disseminate information about viruses. I’ve summarized my use of this format in an article entitled “Social media and microbiology education“, which you can find at the open-access journal PLoS Pathogens. In addition to writing about viruses on virology blog, I also host and produce five podcasts: This Week in Virology, This Week in Parasitism, This Week in Microbiology, This Week in Evolution, and Urban Agriculture. You can find them all on iTunes or at MicrobeTV. I teach a virology course each spring at Columbia University, and I post videocasts of each lecture at the course website, at YouTube, at iTunes University, and at Coursera.
If you would like to learn about our work on viruses in more detail, please visit my website at Columbia University, or my Wikipedia page. You might also like to follow me on Twitter or Google+, where I often provide links to interesting stories about viruses; on YouTube, where I posts videos about viruses; or on Instagram, or the This Week in Virology page on Facebook. I have also written about my work on this site; links to some of these articles are provided below.
Thirty years in my laboratory at Columbia University
Edwin D. Kilbourne, MD, 1920-2011 (his influence on my career)
Thirty years of infectious enthusiasm
Transgenic mice susceptible to poliovirus
Viruses and journalism: Poliovirus, HIV, and sperm
Viruses and journalism: Off-the-shelf chemicals
Disclaimers
All of the opinions that I write on this blog are mine, and in no way represent the views of my employer, Columbia University. This information is provided for educational purposes only, and should not be considered medical advice. If you think you are sick, see your doctor. Links to other sites do not constitute endorsements of those sites.
Vincent Racaniello
Interesting comments and information that demonstrate our ignorance. For more than 40 years, I have only warned members of my profession about treatment-resistant bacteria and fungus and have not given much importance to virus infections. I assumed scientists and doctors know viruses mutilate, jump from animals or plants and infect humans. They also transfer information from one organism to another and so take a few seconds to create a stronger and more intelligent bug that multiply and spread faster.
In 2019, the healthcare providers, our leaders inflicted fear of hospitalisation and death to protect their institutions and investment. Lockdowns and quarantines to help reduce demand, and it took a few months to develop tests. This callous attitude only helped the virus spread, and secondary bacterial infections killed more people. We must be honest, share knowledge and help people conquer the fear of infections, stop using chemicals and claim vaccination will help us revert to life as it was in the past; if not, the situation will only worsen.
Let me explain how I imagine viruses are and why we must step out of the box to help bring an end to the crisis that is destroying the life of humans on earth.
Viruses are like spores, pollens or dust that enter and exit our bodies every time we breathe. They are like the computer software update. They are essential because they are the building blocks of life. Whether we like it or not, they must infect every human on earth. Once they enter, they change the code in our DNA and help open the gates of cells to allow bacteria, fungus and chemicals to enter and exit. These bacteria are like the computer (nucleus) operators, making cells perform their function.
The way we think, act, behave, and function depends on the bacteria colonised in and on our bodies soon after birth. I have tested this hypothesis numerous times and found they are true.
By simply changing the group of children playing with my daughter, I could change the way she thinks and acts, so it’s not the genes (DNA) the is important but the operator of the computer (nucleus) in each cell that makes who you are, what you believe and what you do.
When mitochondria (virus) enter a procaryote, eucaryote is formed, which is the ancestor of every living soul on earth. This symbiotic relationship between organisms is what we must adapt to survive. The era of kill, conquer and rule must come to an end if we humans want to survive; if not, what Issac Newton said will turn out to be true.
I may be wrong, but hope this comment will stirup a debate and help us learn more and understand what life is all about
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I’m familiar with electroporating pathogens with a H.R.C. zapper. (9 volts).
I’m curious if you have tested this method yourself as a means of eliminating pathogens and or recognize neutralizing bacteria with colloidal silver @ 10ppm?
Very truly yours PJ
When will virology conduct the required negative control experiments on the existence of viruses? To date no such experiments have been performed, as admitted in 2014 by Professor Andreas Podbielski from University of Rostock, “I have to expressly clarify that one cannot provide evidence in the classical sense in biology as one can in mathematics or physics. In biology one can only gather clues, which at some point in time in their entirety attain probative value.“
In fact, such control experiments have been carried out where the cell cultures exhibit the same pathology as claimed by virology when the cell cultures are ‘infected’ with a virus, proving the non-existence of viruses, but proving the existence of exosomes.
Your thoughts on this shocking scientific fraud would be appreciated.
What is the difference between a quasi-species and virus variants and strain?
How does Virology.ws engage with its audience, and what resources are available for individuals interested in learning more about virology on the website?
Autophagy is a process involving the structure of the cell itself, through the lysosomal machinery, responsible for the transport of damaged organelles, misfolded proteins, and other macromolecules to lysosomes for degradation and reuse of evolutionally conserved processes. Not a chemistry company: https://www.all-chemistry.com/index
The origins of viruses in the evolutionary history of life are unclear: some may have evolved from plasmids—pieces of DNA that can move between cells—while others may have evolved from bacteria. In evolution, viruses are an important means of horizontal gene transfer, which increases genetic diversity in a way analogous to sexual reproduction.[9] Viruses are considered by some biologists to be a life form, because they carry genetic material, reproduce, and evolve through natural selection, although they lack the key characteristics, such as cell structure, that are generally considered necessary criteria for defining life. Because they possess some but not all such qualities, viruses have been described as “organisms at the edge of life” and as replicators.
Quoted from wiki
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This helps tremendously to solve the puzzle. Thank you.
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I want to share this great testimony to the world on how Dr Osato cured me from Herpes2 with his herbs, I was nervous when I first contacted him about the cure for HSV2 but I decided to give him a try because I was desperate to get cured and be free from HSV2. Dr Osato prepared the cure and sent it to me through UPS,which I used just the way Dr Osato instructed me and thank God today I am a beneficiary of this cure. I went back to the hospital after 14days of taking the herbs and I tested Herpes2 Negative. So I will tell you all who are looking for a cure to his/her HSV1&2 that Dr Osato took research before he could finally get the solution to it and a lot of people are benefiting from him right now. He also cured my friend from HPV. Dr Osato heals with natural herbs. Please i urge you to contact him now through his website https://osatoherbalcure.wordpress.com and he is capable of curing HIV/AIDS, HERPES, HPV, HSV1&2, CANCER of all kinds,DIABETES and so many other infections.
I want to share this great testimony to the world on how Dr Osato cured me from Herpes2 with his herbs, I was nervous when I first contacted him about the cure for HSV2 but I decided to give him a try because I was desperate to get cured and be free from HSV2. Dr Osato prepared the cure and sent it to me through UPS,which I used just the way Dr Osato instructed me and thank God today I am a beneficiary of this cure. I went back to the hospital after 14days of taking the herbs and I tested Herpes2 Negative. So I will tell you all who are looking for a cure to his/her HSV1&2 that Dr Osato took research before he could finally get the solution to it and a lot of people are benefiting from him right now. He also cured my friend from HPV. Dr Osato heals with natural herbs. Please i urge you to contact him now through his website https://osatoherbalcure.wordpress.com and he is capable of curing HIV/AIDS, HERPES, HPV, HSV1&2, CANCER of all kinds,DIABETES and so many other infections
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Hello everyone I’m here to share how a traditional herbalist called Excel cured me from genital herpes virus with his ancient herbal medicine’ I will forever be grateful to him for curing me from such virus when I thought it was all over’ today I am happy with my life after the lab tests confirm severally that the virus of 3 years is gone, I have never in my life believed that HERPES VIRUS could be cured by herbal medicine. you also try him out’ it can as well work for you so reach him today via his website. Excelherbalcure.com
NATURAL HERBS IS THE REAL DEAL IN CURING HERPES-1&2, HIV/AIDS, HPV, DIABETES AND CANCER..Contact Dr Osato to get the natural herbs to cure yourself from that horrible disease/virus.. I got the herbs from Dr Osato and I made use of it with the instructions he gave to me on how to use the natural herbal product, after usage I went for a checkup and my result was Negative and all the symptoms of herpes were completely gone from my body. I was cured from herpes-1&2 after using Dr Osato natural herbal medicine. You can contact Dr Osato on his website https://osatoherbalcure.wordpress.com
I can’t still believe that I got cured from Genital Herpes through herbal treatment from Dr Excel who I met through the internet, I actually couldn’t believe it at first because it sounded impossible to me knowing how far I have gone just to get rid of it. Dr Excel send me his medicine which I took as instructed and here I am living a happy life once again after testing negative’ and I don’t experience the symptoms no more, a big thanks to Dr Excel, I am sure there are many herbal doctors out there but Dr Excel did it for me, contact him today by visiting his website: https://excelherbalcure.com
Here is my testimony on how to get cured from HSV1&2. I got diagnose of HSV-2 and I have been taking pills to prevent an outbreak. I never stop searching for a cure because I strongly believe that there is something somewhere that can get rid of it completely and in February this year, I ran through some comments on a blog about Dr Osato herbal cure and a lot of people commented about him having the herbs that can get rid of herpes completely. I was excited and I contacted Dr Osato and ordered the cure for myself and he sent it to me through UPS and gave me instructions on how to take it which I rightly followed and behold I went for checkup after two weeks of taking the herbs and my result shows NEGATIVE. My doctor confirmed with me that I am totally clear from HSV-2. You can as well contact Dr Osato to get the herbal cure from him. His website is https://osatoherbalcure.wordpress.com
What a great joy in my heart to share this to the entire public on how Dr Osato cured me from herpes1&2 with his herbs, I never believe it will work because the doctors keep saying there is no cure but I was desperate and needed to get this thing out of my body. I saw a comment online testifying how Dr Osato cure her from herpes and hpv and i contact Dr Osato and explain my problem to him and he prepare the cure and send it to me through UPS,which i use it just the way He instructed me and thank God today am a beneficiary to these cure. I went to my doctor for a checkup after 14days of taking the herbs and I did a blood test which i tested Herpes1&2 Negative and my doctor booked me for another appointment after 4 weeks to confirm my result and i retested again after 4 weeks and my result was still Negative and my doctor assured me that the virus is completely gone from my system. So I will tell you all who are looking for a cure to his/her HIV/AIDS and HERPES that Dr Osato took research before he could finally get the solution to it and a lot of people are benefiting from him right now. He also cured my Uncle and his wife from HPV. Dr Osato heals with natural herbs. Please i urge you to contact him now through his website https://osatoherbalcure.wordpress.com and he is capable of curing HIV/AIDS, HERPES, HPV, HSV1&2, COLD SORE, CANCER of all kinds,DIABETES and so many other infections
Greatest thanks to Dr Oyagu for his herbal drugs that he prepared for me and when i start using it in just 2weeks i was completely cured and that ended my HERPES SIMPLEX 1&2 DISEASE i am so happy and grateful to Dr Oyagu . after reading about him on a testimony of Jason Cash on a blogger. i knew suddenly Dr Oyagu was the right Doctor to cure my HERPES SIMPLEX 1&2 DISEASE. i discuss with Dr Oyagu and he prepared a herbal medicine for me and when it got sent to me in south korean . i used the herbal medicine and 2weeks and i went to check up again. after 15years of suffering from HERPES SIMPLEX 1&2 at last i am smiling once again. Dr Oyagu also has remedy to others disease like COLD SORES,HIV/AIDS,DIABETES.CANCER,HIGH BLOOD PRESSURE AND MANY MORE. I oblige everyone to contact this powerful herbalist Dr Oyagu and be free from your suffering. contact his Email:Oyaguherbalhome@ gmail. com
I want to share this great testimony to the world on how Dr Osato cured me from Herpes-1&2 with his herbs, I was nervous when I first contacted him about the cure for HSV, but I decided to give him a try because I was desperate to get cured and be free from HSV. Dr Osato prepared the cure and sent it to me through UPS,which I used just the way he instructed me and thank God today I am a beneficiary of this cure. I went back to the hospital after 14days of taking the herbs and I tested Herpes-1&2 Negative. So I will tell you all who are looking for a cure to his/her HSV1&2 that Dr Osato took research before he could finally get the solution to it and a lot of people are benefiting from him right now. He also cured my friend from HPV. Dr Osato heals with natural herbs. Please i urge you to contact him now through his website is https://osatoherbalcure.wordpress.com