The TWiV team speaks with Patrick Moore about his discovery, with Yuan Chang, of two human tumor viruses, Kaposi’s sarcoma herpesvirus and Merkel cell polyomavirus.
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Links for this episode:
- Chang-Moore laboratory at University of Pittsburgh
- Representational difference analysis (Science)
- KSHV: Forgotten but not gone (Blood)
- Why do viruses cause cancer? (Nat Rev Cancer)
- Merkel cell carcinoma review (Ann Rev)
- Clonal integration of a polyomavirus in Merkel carcinoma (Science)
- T antigen mutations in Merkel polyomavirus (PNAS)
- Merkel polyomavirus small t is an oncoprotein (J Clin Inves)
- Suggest a topic for the 2012 ASM General Meeting
- TWiV on Facebook
- Letters read on TWiV 160
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Great episode! It is astounding that infections are causative to so many cases of cancer while this fact is neither represented in the media, nor in funded research. If you look at a list not limited to cancer the association between infection and chronic disease gets even stronger.
http://en.wikipedia.org/wiki/List_of_human_diseases_associated_with_infectious_pathogens